Virtual issue on Development / Stem cell


Most recent articles published on Development / Stem cell [2013] [2012] [2011] [2010] [2009] [2008] [2007] [2006] [2005]

Recent Articles Published on Development / Stem cell


Melanomas of unknown primary have a mutation profile consistent with cutaneous sun exposed melanoma
Ken Dutton-Regester, Hojabr Kakavand, Lauren G. Aoude, Mitchell S. Stark, Michael G. Gartside, Peter Johansson, Linda O'Connor, Cathy Lanagan, Varsha Tembe, Gulietta M. Pupo, Lauren Haydu, Christopher W. Schmidt, Graham J. Mann, John F. Thompson, Richard A. Scolyer and Nicholas K. Hayward

Links between Schwann cells and melanocytes in development and disease
Catherine D. Van Raamsdonk and Mugdha Deo

Irradiance, but not fluence, plays a crucial role in UVB-induced immature pigment cell development: new insights for efficient UVB phototherapy
Cheng-Che E. Lan, Hsin-Su Yu, Jian-He Lu, Ching-Shuang Wu and Hsiao-Chi Lai

Differential expression and tumor necrosis factor-mediated regulation of TNFRSF11b/osteoprotegerin production by human melanomas (pages 571–579)
Janine L. Oliver, Matthew P. Alexander, Allison G. Norrod, Irene M. Mullins and David W. Mullins

Hermansky–Pudlak syndrome: pigmentary and non-pigmentary defects and their pathogenesis
Ai-Hua Wei and Wei Li

Chk1 is essential for the development of murine epidermal melanocytes (pages 580–585)
Joanne Smith, Lionel Larue and David A. Gillespie

Slc45a2 and V-ATPase are regulators of melanosomal pH homeostasis in zebrafish, providing a mechanism for human pigment evolution and disease (pages 205–217)
Christopher M. Dooley, Heinz Schwarz, Kaspar P. Mueller, Alessandro Mongera, Martina Konantz, Stephan C. F. Neuhauss, Christiane Nüsslein-Volhard and Robert Geisler


Postnatal lineage mapping of follicular melanocytes with the Tyr::CreERT2 transgene
Melissa L. Harris and William J. Pavan

Hearing Dysfunction in Heterozygous MitfMi-wh/+ Mice, a Model for Waardenburg Syndrome Type 2 and Tietz Syndrome
Christina Ni, Deming Zhang, Lisa A. Beyer, Karin E. Halsey, Hideto Fukui, Yehoash Raphael, David F. Dolan and Thomas J. Hornyak

Adam10 haploinsufficiency causes freckle-like macules in Hairless mice
Tharmarajah Grace, Faas Laura, Reiss Karina, Saftig Paul, Young Antony and Catherine D. Van Raamsdonk

SOX2 Modulates Levels of MITF in Human Embryonic Stem Cell - Derived Neural Crest, Normal Human Melanocytes, and Melanoma Lines In Vitro.
Flavio Cimadamore, Meera Shah, Alejandro Amador-Arjona, Encarnacion, M. Peran, Connie Chen and Alexey V. Terskikh

Pax3GFP,a new reporter for the melanocyte lineage, highlights novel aspects of PAX3 expression in the skin.
Johanna Djian-Zaouche, Cécile Campagne, Edouard Reyes-Gomez, Stéphanie Gadin-Czerw, Florence Bernex, Anne Louise, Frédéric Relaix, Margaret Buckingham, Jean-Jacques Panthier and Geneviève Aubin-Houzelstein

Characterization of two novel small molecules targeting melanocyte development in zebrafish embryogenesis
Lu Chen, Xi Ren, Fang Liang, Song Li, Hanbing Zhong and Shuo Lin

Gene expression changes in melanoma metastases in response to high-dose chemotherapy during isolated limb perfusion
Jasper Wouters, Marguerite Stas, Olivier Govaere, Kathleen Van den Eynde, Hugo Vankelecom and Joost J. van den Oord

Bimodal effect of retinoic acid on melanocyte differentiation identified by time-dependent analysis
Yu Inoue, Seiji Hasegawa, Takaaki Yamada, Yasushi Date, Hiroshi Mizutani, Satoru Nakata, Kayoko Matsunaga and Hirohiko Akamatsu

Constitutive gray hair in mice induced by melanocyte-specific deletion of c-Myc
Irina Pshenichnaya, Karine Schouwey, Marzia Armaro, Lionel Larue, Paul S. Knoepfler, Robert N. Eisenman, Andreas Trumpp, Véronique Delmas and Friedrich Beermann

Changing clothes easily: connexin41.8 regulates skin pattern variation
Masakatsu Watanabe and Shigeru Kondo

Small molecule screening identifies targetable zebrafish pigmentation pathways
Sarah Colanesi, Kerrie L. Taylor, Nicholas D. Temperley, Pia R. Lundegaard, Dong Liu, Trista E. North, Hironori Ishizaki, Robert N. Kelsh and E. Elizabeth Patton


Melanocyte stem cells: a melanocyte reservoir in hair follicles for hair and skin pigmentation
Emi K. Nishimura

Generation of melanocytes from neural crest cells
Lukas Sommer

Dermis-derived stem cells: a source of epidermal melanocytes and melanoma?
Susan E. Zabierowski, Mizuho Fukunaga-Kalabis, Ling Li and Meenhard Herlyn

ABCB1 identifies a subpopulation of uveal melanoma cells with high metastatic propensity
Solange Landreville, Olga A. Agapova, Zachary T. Kneass, Christian Salesse and J. William Harbour    

The new paradigm: retinal pigment epithelium cells generated from embryonic or induced pluripotent stem cells
Kapil Bharti, Sheldon S. Miller and Heinz Arnheiter

Sex-specific coloration for display and camouflage
Heinz Arnheiter

Sox proteins in melanocyte development and melanoma 
Melissa L. Harris, Laura L. Baxter, Stacie K. Loftus and William J. Pavan

Allele-specific genetic interactions between Mitf and Kit affect melanocyte development 
Bin Wen, Yu Chen, Huirong Li, Jing Wang, Jie Shen, Aobo Ma, Jia Qu, Keren Bismuth, Julien Debbache, Heinz Arnheiter and Ling Hou

Melanocytes don't always take the high road
Hun-Way Hwang, Willam J. Pavan

Melanoma and viagra: an unexpected connection
Devarati Mitra, Kathleen C. Robinson and David E. Fisher

Melanoma: is hair the root of the problem?
Angela M. Gomez Garcia, Christine E. McLaren and Frank L. Meyskens Jr.

Different types of DNA damage play different roles in the etiology of sunlight-induced melanoma
David L. Mitchell and André A. Fernandez

Functionally distinct melanocyte populations revealed by reconstitution of hair follicles in mice
Hitomi Aoki, Akira Hara, Tsutomu Motohashi, Masatake Osawa and Takahiro Kunisada

The deceptive nature of UVA tanning versus the modest protective effects of UVBtanning on human skin
Yoshinori Miyamura, Sergio G. Coelho, Kathrin Schlenz, Jan Batzer, Christoph Smuda, Wonseon Choi, Michaela Brenner, Thierry Passeron, Guofeng Zhang, Ludger Kolbe, Rainer Wolber and Vincent J. Hearing

In vitro differentiation of retinal pigment epithelium from adult retinal stemcells
Claudia Aruta, Francesca Giordano, Anna De Marzo, Antonella Comitato, Graça Raposo, Emeline F. Nandrot and Valeria Marigo

The mouse pink-eyed dilution allele of the P-gene greatly inhibits eumelanin but notpheomelanin synthesis
Tomohisa Hirobe, Shosuke Ito and Kazumasa Wakamatsu


Cancer stem cells versus phenotype-switching in melanoma
Keith S. Hoek and Colin R. Goding

Differential roles of the pRb and Arf/p53 pathways in murine naevus and melanoma genesis
Blake Ferguson, H. Konrad Muller, Herlina Y. Handoko, Kiarash Khosrotehrani, Friedrich Beermann, Elke Hacker, H. Peter Soyer, Marcus Bosenberg and Graeme J. Walker

p53 prevents progression of nevi to melanoma predominantly through cell cycle regulation
Tamara Terzian, Enrique C. Torchia, Daisy Dai, Steven E. Robinson, Kazutoshi Murao, Regan A. Stiegmann, Victoria Gonzalez, Glen M. Boyle, Marianne B. Powell, Pamela M. Pollock, Guillermina Lozano, William A. Robinson, Dennis R. Roop and Neil F. Box

Downregulation of SIK2 expression promotes the melanogenic program in mice
Nanao Horike, Ayako Kumagai, Yuko Shimono, Tomoko Onishi, Yumi Itoh, Tsutomu Sasaki, Kazuo Kitagawa, Osamu Hatano, Hiroaki Takagi, Teruo Susumu, Hiroshi Teraoka, Ken-ichi Kusano, Yasuo Nagaoka, Hidehisa Kawahara and Hiroshi Takemori

The aryl hydrocarbon receptor (AHR), a novel regulator of human melanogenesis
Sandra Luecke, Maria Backlund, Bettina Jux, Charlotte Esser, Jean Krutmann and Agneta Rannug

Sunscreen prevention of melanoma in man and mouse
Heather L. P. Klug, Janet A. Tooze, Cari Graff-Cherry, Miriam R. Anver, Frances P. Noonan, Thomas R. Fears, Margaret A. Tucker, Edward C. De Fabo and Glenn Merlino

Decreased heme oxygenase-1 expression distinguishes human melanomas from melanocytic nevi
Sun A Jin, Jae-Jeong Park, Jee-Bum Lee, Seung-Chul Lee and Sook Jung Yun

Quantitative measurement of circulating lymphoid-specific helicase (HELLS) gene transcript: a potential serum biomarker for melanoma metastasis
Hye-Eun Kim, James T. Symanowski, Erika E. Samlowski, Jason Gonzales and Byungwoo Ryu

TRP-ing off the p53 apoptotic switch
Afshan Ahmed and Margaret Ashcroft

Smoke and miRrors: pseudogenes tricking miRNAs
Meifan Chen

Not quite as old as the sun
Estela E. Medrano

Genome-wide association studies of pigmentation and skin cancer: a review and meta-analysis
Meg R. Gerstenblith, Jianxin Shi and Maria Teresa Landi

The evolving concept of ‘melano-miRs’– microRNAs in melanomagenesis
Daniel W. Mueller and Anja-Katrin Bosserhoff

The unfolded protein response in melanocytes: activation in response to chemical stressors of the endoplasmic reticulum and tyrosinase misfolding
Prashiela Manga, Sabina Bis, Kristen Knoll, Beremis Perez and Seth J. Orlow

Autochthonous primary and metastatic melanomas in Hgf-Cdk4R24C mice evade T-cell-mediated immune surveillance
Jennifer Landsberg, Evelyn Gaffal, Mira Cron, Judith Kohlmeyer, Marcel Renn and Thomas Tüting

Melanoma stem cells – are there devils in the detail?
Mark Shackleton

Of patches, blotches, speckles and stripes
Heinz Arnheiter

Sex-specific coloration for display and camouflage
Heinz Arnheiter

Shades of meaning: the pigment-type switching system as a tool for discovery
Will P. Walker and Teresa M. Gunn

Sox proteins in melanocyte development and melanoma 
Melissa L. Harris, Laura L. Baxter, Stacie K. Loftus and William J. Pavan

Are stem cell niches shared for skin cancers?
Neil F. Box, Enrique C. Torchia and Dennis R. Roop

Melanocyte homeostasis in vivo tolerates Rb1 loss in a developmentally independent fashion
Ian D. Tonks, Arne W. Mould, Wayne A. Schroder, Elke Hacker, Marcus Bosenberg, Nicholas K. Hayward, Graeme J. Walker and Graham F. Kay

Cul1 expression is increased in early stages of human melanoma
Guangdi Chen, Yabin Cheng, Magdalena Martinka and Gang Li

The quest for the melanoma stem cell: still more questions than answers
Florian Rambow and Lionel Larue

What tumor vessels can tell us
Sunyoung Lee

Chemokine modulation of the tumor microenvironment
Ann Richmond

β-Catenin regulates melanocyte dendricity through the modulation of PKCζ and PKCδ
Jin-Hwa Kim, Kyung-Cheol Sohn, Tae-Young Choi, Mi Yoon Kim, Hideya Ando, Sun Ja Choi, Sooil Kim, Young Ho Lee, Jeung-Hoon Lee, Chang Deok Kim and Tae-Jin Yoon

Genome-wide analysis of POU3F2/BRN2 promoter occupancy in human melanoma cells reveals Kitl as a novel regulated target gene
Dominique Kobi, Anne-Lise Steunou, Doulaye Dembélé, Stéphanie Legras, Lionel Larue, Laurence Nieto and Irwin Davidson

Allele-specific genetic interactions between Mitf and Kit affect melanocyte development 
Bin Wen, Yu Chen, Huirong Li, Jing Wang, Jie Shen, Aobo Ma, Jia Qu, Keren Bismuth, Julien Debbache, Heinz Arnheiter and Ling Hou

Human malignant melanoma harbours a large fraction of highly clonogenic cells that do not express markers associated with cancer stem cells
Lina Prasmickaite, Nirma Skrbo, Hanne K. Høifødt, Zhenhe Suo, Olav Engebråten, Hans P. Gullestad, Steinar Aamdal, Øystein Fodstad and Gunhild M. Mælandsmo

Ex vivo live imaging of melanoblast migration in embryonic mouse skin
Richard L. Mort, Leonard Hay and Ian J. Jackson

UVA tanning is involved in the increased incidence of skin cancers in fair-skinned young women
Sergio G. Coelho and Vincent J. Hearing

Inducible expression of V600EBraf using tyrosinase-driven Cre recombinase results in embryonic lethality
Nathalie Dhomen, Silvy Da Rocha Dias, Robert Hayward, Lesley Ogilvie, Douglas Hedley, Veronique Delmas, Afshan McCarthy, Deborah Henderson, Caroline J. Springer, Catrin Pritchard, Lionel Larue and Richard Marais

The new paradigm: Retinal pigment epithelium cells generated from embryonic stem cells or induced pluripotent cells
Kapil Bharti, Sheldon S. Miller and Heinz Arnheiter

Interpretation of complex phenotypes: Lessons from the Mitf gene
Eiríkur Steingrímsson

The discovery of the microphthalmia locus and its gene, Mitf
Heinz Arnheiter

Sox proteins in melanocyte development and melanoma
Melissa L. Harris, Laura L. Baxter, Stacie K. Loftus, William J. Pavan

Sex-specific coloration for display and camouflage
Heinz Arnheiter

Allele-specific genetic interactions between Mitf and Kit affect melanocyte development
Bin Wen, Yu Chen, Huirong Li, Jing Wang, Jie Shen, Aobo Ma, Jia Qu, Keren Bismuth, Julien Debbache, Heinz Arnheiter, Ling Hou

Ex-vivo live imaging of melanoblast migration in embryonic mouse skin
Richard L. Mort, Leonard Hay, Ian J. Jackson

Melanocytes don't always take the high road
Hun-Way Hwang, Willam J. Pavan



Unique transforming properties of Notch1 in human melanocytes
Barbara Bedogni and Marianne Broome Powell

Involvement of ABC transporters in melanogenesis and the development of multidrug resistance of melanoma
Kevin G. Chen, Julio C. Valencia, Jean-Pierre Gillet, Vincent J. Hearing and Michael M. Gottesman

Stem cell factor rescues tyrosinase expression and pigmentation in discreet anatomic locations in albino mice
Jillian C Vanover, Malinda L Spry, Laura Hamilton, Kazumasa Wakamatsu, Shosuke Ito and John A D’Orazio

Laminin-421 produced by lymphatic endothelial cells induces chemotaxis for human melanoma cells 
Noriko Saito, Jun-ichi Hamada, Hiroshi Furukawa, Arata Tsutsumida, Akihiko Oyama, Emi Funayama, Akira Saito, Tsutomu Tsuji, Mitsuhiro Tada, Tetsuya Moriuchi and Yuhei Yamamoto

The tyrosinase promoter is active in a subset of vagal neural crest cells during early development in mice
Isabel Puig, Ichiro Yajima, Jacky Bonaventure, Véronique Delmas and Lionel Larue

Melanocytes don't always take the high road
Hun-Way Hwang, Willam J. Pavan

15-year quest in search for MITF target genes
Yann Cheli, Mickael Ohanna, Robert Ballotti, Corine Bertolotto

H19 RNA downregulation stimulated melanogenesis in melasma
Nan-Hyung Kim, Chang-Hoon Lee, Ai-Young Lee

Functional role of MITF phosphorylation. In vivo veritas? 
Corine Bertolotto, Robert Ballotti

Classic versus non-classic: A survival Kit for life in the skin 
Shigeyuki Uehara, Akiha Kawasaki, Hiroaki Yamamoto

NRG1 / ERBB3 signaling in melanocyte development and melanoma: inhibition of differentiation and promotion of proliferation 
Kristina Buac, Mai Xu, Julie Cronin, Ashani T. Weeraratna, Stephen M. Hewitt, William J. Pavan

Genetics of human iris colour and patterns 
Richard A. Sturm, Mats Larsson

Comparison of melanoblast expression patterns identifies distinct classes of genes 
Stacie K. Loftus, Laura L. Baxter, Kristina Buac, Dawn E. Watkins-Chow, Denise M. Larson, William J. Pavan

Evidence that stress to the epidermal barrier influenced the development of pigmentation in humans
Peter M. Elias, Gopinathan Menon, Bruce K. Wetzel, John (Jack) W. Williams

Sphingolipid-mediated restoration of Mitf expression and repigmentation in vivo in a mouse model of hair graying
Bidisha Saha, Suman Kumar Singh, Shampa Mallick, Rabindranath Bera, Pijush K. Datta, Mriganka Mandal, Syamal Roy, Ranjan Bhadra



Melanocyte-lineage expression of Cre recombinase using Mitf regulatory elements
Azita Alizadeh, Karen R. Fitch, Colleen M. Niswender, G. Stanley McKnight and Gregory S. Barsh
February 2008

Both Notch1 and Notch2 contribute to the regulation of melanocyte homeostasis
Keiki Kumano, Shigeo Masuda, Masataka Sata, Toshiki Saito, Suk-young Lee, Mamiko Sakata-Yanagimoto, Taisuke Tomita, Takeshi Iwatsubo, Hideaki Natsugari, Mineo Kurokawa, Seishi Ogawa and Shigeru Chiba
February 2008


The tyrosinase enhancer is activated by Sox10 and Mitf in mouse melanocytes
Fabien Murisier, Sabrina Guichard and Friedrich Beermann
June 2007

Evolutionary sequence comparison of the Mitf gene reveals novel conserved domains
Jón Hallsteinn Hallsson, Benedikta S. Haflidadóttir, Alexander Schepsky, Heinz Arnheiter and Eiríkur Steingrímsson
June 2007

Informatic and genomic analysis of melanocyte cDNA libraries as a resource for the study of melanocyte development and function
Laura L. Baxter, Benjamin J. Hsu, Lowell Umayam, Tyra G. Wolfsberg, Denise M. Larson, Martin C. Frith, Jun Kawai, Yoshihide Hayashizaki, Piero Carninci and William J. Pavan
June 2007

A mouse model of Waardenburg syndrome type IV resulting from an ENU-induced mutation in endothelin 3
Ivana Matera, Jody L. Cockroft, Jennifer L. Moran, David R. Beier, Dan Goldowitz and William J. Pavan
June 2007


The other pigment cell: specification and development of the pigmented epithelium of the vertebrate eye
Kapil Bharti, Minh-Thanh T. Nguyen, Susan Skuntz, Stefano Bertuzzi, Heinz Arnheiter
October 2006

Induction of melanocytes from embryonic stem cells and their therapeutic potential
Tsutomu Motohashi, Hitomi Aoki, Naoko Yoshimura, Takahiro Kunisada
August 2006


Pigment pattern formation in the medaka embryo
M. Lynn Lamoreux, Robert N. Kelsh, Yuko Wakamatsu and Kenjiro Ozato
April 2005

Secrets to a healthy Sox life: lessons for melanocytes
Michael Wegner
April 2005

Comparative study of eye defective worm ' menashi ' and regenerating wild-type in planarian, Dugesia ryukyuensis
Yukiko Sato, Kazuya Kobayashi, Midori Matsumoto, Motonori Hoshi and Sumiko Negishi
April 2005

WNT1 and WNT3a promote expansion of melanocytes through distinct modes of action
Karen Joyce Dunn, Matthew Brady, Christina Ochsenbauer-Jambor, Sara Snyder, Arturo Incao and William J. Pavan
June 2005

Ednrb2 orients cell migration towards the dorsolateral neural crest pathway and promotes melanocyte differentiation
Patrick Pla, Christophe Alberti, Olga Solov'eva, Manijeh Pasdar, Takahiro Kunisada and Lionel Larue
June 2005

Establishment of a Kit-negative cell line of melanocyte precursors from mouse neural crest cells
Yoko Kawa, Yoshinao Soma, Masayuki Nakamura, Masaru Ito, Tamihiro Kawakami, Takako Baba, Kuniko Sibahara, Kayoko Ohsumi, Shiho Ooka, Hidenori Watabe, Hirotake Ono, Eri Hosaka, Satoko Kimura, Tsuneto Kushimoto and Masako Mizoguchi
June 2005

Novel expression patterns of Pax3/Pax7 in early trunk neural crest and its melanocyte and non-melanocyte lineages in amniote embryos
Ana M a Lacosta, Pedro Muniesa, Jesús Ruberte, Manuel Sarasa and Luis Domínguez
August 2005

Melanocytes in conditional Rb-/- mice are normal in vivo but exhibit proliferation and pigmentation defects in vitro
Ian D. Tonks, Elke Hacker, Nicole Irwin, H. Konrad Muller, Patricia Keith, Arne Mould, Anna Zournazi, Sandra Pavey, Nicholas K. Hayward, Graeme Walker and Graham F. Kay
August 2005

Sumoylation modulates transcriptional activity of MITF in a promoter-specific manner
Hideki Murakami and Heinz Arnheiter
August 2005

MITF and cell proliferation: the role of alternative splice forms
Keren Bismuth, Dragan Maric and Heinz Arnheiter
October 2005

Pax3 target gene recognition occurs through distinct modes that are differentially affected by disease-associated mutations
Gareth N. Corry and D. Alan Underhill
December 2005

Blackwell Publishing

Blackwell Publishing